Reposted: Granulocyte Concentrates Prepared from Reveos Buffy Coats

The Reveos buffy coat is not approved for clinical use.  In my laboratory, I have offered this discard product to the stem cell laboratory and researchers as a quality control QC and a substrate to extract CD34+ cells for expansion and modification.

In this article (abstract attached) from Transfusion and Apheresis Science 59 (2020) 102682, the authors study pools of ABO-identical Reveos buffy coats for their granulocyte functionality and as a possible emergency replacement for granulocyte concentrates when the latter are not available.

I want to thank Terumo BCT (Brussels, Belgium) for referring me to this article and to the authors for a very interesting paper.