As I designed in Medinfo, this is a much simpler algorithm than HCV and uses an HTLV-1/HTLV-2 screening test and a confirmatory linear immunoblot assay LIA that can discriminate between type 1 and type 2. If there is an indeterminate result, a repeat test is ordered after 6 months:
- HTLV 1/2 Testing:
- HTLV Antibodies positive, then do HTLV-InnoLIA:
- HTLV InnoLIA positive for HTLV-1 and/or HTLV-2: refer to Infectious Disease clinic
- HTLV InnoLIA indeterminate or negative, repeat HTLV Ab and HTLV InnoLIA testing after 6 months
- Repeat HTLV Testing After 6 Months:
- HTLV 1/2 antibodies positive, permanent deferral and do HTLV InnoLIA
- HTLV 1/2 antibodies indeterminate, permanent deferral and do HTLV InnoLIA
- HTLV InnoLIA positive for HTLV-1 or HTLV-2: refer to Infectious Disease clinic
- HTLV InnoLIA indeterminate, donor permanently deferred.
- Issue letter HTLV-Not Confirmed
- HTLV 1/2 Ab negative and HTLV InnoLIA negative, reenter donor.
- HTLV Antibodies positive, then do HTLV-InnoLIA:
This is translated into the following Medinfo processes:

To Be Continued:
15/8/20